15-Nooca HR-HPV mRNA Ogaanshaha - Wuxuu aqoonsadaa joogitaanka iyo waxqabadka HR-HPV

Kansarka ilmo-galeenka, oo ah sababta ugu badan ee dhimashada haweenka adduunka, waxaa inta badan keena caabuqa HPV. Awoodda oncogenic ee caabuqa HR-HPV waxay ku xiran tahay muujinta kororka ee E6 iyo E7. Barootiinada E6 iyo E7 waxay ku xidhan yihiin borotiinada xakamaynta burada p53 iyo pRb siday u kala horreeyaan, waxayna wadaan kordhinta unugyada ilmagaleenka iyo isbeddelka.

Si kastaba ha ahaatee, baaritaanka HPV DNA wuxuu xaqiijinayaa jiritaanka fayraska, ma kala saaro inta u dhaxaysa caabuqyada qarsoon iyo kuwa firfircoon. Taas bedelkeeda, ogaanshaha qoraalada HPV E6/E7 mRNA waxay u adeegtaa sidii biomarker gaar ah oo muujinta fayraska oncogene-ka ee firfircoon, sidaas awgeed, waa saadaaliye sax ah oo ku saabsan neoplasia intraepithelial intraepithelial (CIN) ama kansarka faafa.

HPV E6/E7 mRNATijaabadu waxa ay faa'iidooyin muhiim ah ka bixisaa ka hortagga kansarka ilma-mareenka:

• Qiimaynta Khatarta Saxda ah: Wuxuu aqoonsadaa infekshannada HPV ee firfircoon, khatarta sare leh, taasoo bixisa qiimayn khatar ah oo ka saxsan marka loo eego baaritaanka HPV DNA.
• Kala soocida wax ku oolka ah: Waxay ku hagtaa daaweeyayaasha inay aqoonsadaan bukaanada u baahan baaritaan dheeri ah, yareynta hababka aan loo baahnayn.
• Aalad Baadhitaan Suuragal ah: Waxa laga yaabaa in ay u adeegto sidii qalab baadhis oo gooni ah mustaqbalka, gaar ahaan dadka khatarta sare leh.
• 15 Noocyada Khatarta Sare leh ee Human Papillomavirus E6/E7 Gene mRNA Detection Kit (Fluorescence PCR) oo ka socota #MMT, si tayo leh u ogaanaya calaamadeeyaha caabuqyada HR-HPV ee horumarsan, waa qalab waxtar u leh baaritaanka HPV iyo/ama maareynta bukaanka.

Tilmaamaha alaabta:

• Caymis buuxa: 15 nooc oo HR-HPV ah oo la xiriira kansarka ilmo galeenka oo daboolay;
• Dareen aad u fiican: 500 koobi/mL;
• Gaar ahaan sareWax dhaqdhaqaaq ah oo iskutallaabta ah oo leh cytomegalovirus, HSV II iyo DNA-da genomic ee aadanaha;
• Kharash-wax-ku-ool ah: Tijaabinta bartilmaameedyada si aad ugu dhow oo xiriir la leh cudurka suurtogalka ah, si loo yareeyo baaritaannada aan loo baahnayn ee kharashyada dheeraadka ah;
• Saxsanaan aad u wanaagsan: IC habka oo dhan;
• Waafaqid ballaaran: Nidaamyada PCR-ga caadiga ah;