Qiimaynta HPV Genotyping sida Biomarkers ogaanshaha halista kansarka ilmo galeenka ilmo-galeenka - Codsiyada ogaanshaha unugyada HPV

Infekshanka HPV wuxuu ku badan yahay dadka galmoodka firfircoon, laakiin infekshanka joogtada ahi wuxuu ku soo baxaa qayb yar oo keliya. Joogitaanka HPV waxay ku lug leedahay khatarta ah inay yeeshaan nabarro hore oo kansar ah iyo, ugu dambeyntii, kansarka ilmo-galeenka

HPVs lama dhaqan gelin karoin vitrohababka caadiga ah, iyo kala duwanaanshiyaha dabiiciga ah ee ballaaran ee jawaab celinta difaaca kaftan ka dib infekshanku wuxuu wax u dhimaa isticmaalka baaritaanka unugyada difaaca jirka ee HPV ee ogaanshaha. Ogaanshaha infekshanka HPV, sidaas darteed, waxaa lagu gaaraa baaritaanka molecular, badiyaa marka la ogaado hiddo-wadaha HPV DNA.

Hadda, noocyo badan oo ganacsi oo kala duwan ayaa jira habab genotyping HPV ah. Xulashada midda ku habboon waxay ku xiran tahay isticmaalka loogu talagalay, sida: cudurrada faafa, qiimeynta tallaalka, ama daraasadaha bukaan-socodka.

Daraasadaha cudurrada faafa, hababka genotyping HPV waxay oggolaadaan in la sawiro nooca faafitaanka gaarka ah.
Qiimaynta tallaalka, qiimaynahani waxay bixinayaan xog ku saabsan isbeddellada baahsanaanta noocyada HPV ee aan lagu darin tallaallada hadda jira, waxayna fududeeyaan dabagalka cudurrada joogtada ah.
Daraasadaha kiliinikada, tilmaamaha caalamiga ah ee hadda jira waxay ku talinayaan isticmaalka baaritaanka hidda-socodka HPV ee haweenka 30 sano iyo ka weyn ee leh cytology taban iyo HR HPV natiijooyin togan, HPV-16 iyo HPV-18 gaar ah. Ogaanshaha HPV iyo takoorida genotypes-ka khatarta hooseeya iyo kuwa hooseeya laba jeer ama ka badan si loo helo bukaanno isku mid ah caabuqyada joogtada ah ee genotype, taasoo keentay maamul caafimaad oo wanaagsan.

Makro & Tijaabada-yar ee xirmooyinka genotyping HPV:

• 14 Noocyada HPV (Genotyping) Qalabka Lagu Ogaado Asiidhka Nucleic (Fluorescence PCR)
• La qaboojiyey-la qallajiyey 14 nooc oo HPV ah (Genotyping) Qalabka lagu ogaado Asiidhka Nukliyeerka (Fluorescence PCR)
• 28 Noocyada HPV (Genotyping) Qalabka lagu ogaado (Fluorescence PCR) (18 HR-HPVs +10 LR-HPVs)
• Qallalan 28 HPV ah (Genotyping) Qalabka lagu ogaado (Fluorescence PCR)

Tilmaamaha alaabta muhiimka ah:

• Ogaanshaha isku mar ah ee genotypes badan hal falcelin;
• Waqtiga gaaban ee PCR ee go'aannada caafimaad ee degdegga ah;
• Noocyo muunado oo badan (kaadi/swab) si loo baaro caabuqa HPV ee raaxada leh oo la heli karo;
• Labada Koontaroolada Gudaha waxay ka hortagaan xaqiiqooyinka beenta ah waxayna xaqiijiyaan isku halaynta imtixaanka;
• Noocyada dareeraha iyo lyophilized ee ikhtiyaarrada macaamiisha;
• Waafaqsanaanta nidaamyada PCR intooda badan ee laqabsiga shaybaarka.