Muunad-ilaa-Jawaab-C. Ogaanshaha Caabuqa Kala Duwan

Maxaa sababa caabuqa C. Diff?

C. Caabuqa kala duwan waxaa sababa bakteeriya loo yaqaanClostridioides difficile (C. difficile), oo badanaa si aan waxyeello lahayn ugu nool xiidmaha. Si kastaba ha ahaatee, marka dheelitirka bakteeriyada mindhicirka la carqaladeeyo, oo badanaa la isticmaalo antibiyootiko ballaaran, C. difficile wuxuu si xad dhaaf ah u kori karaa oo soo saari karaa sun, taasoo keenta caabuq.

Bakteeriyadani waxay ku jirtaa labadasunta keenaiyo qaababka aan sunta ahayn, laakiin noocyada sunta ah oo keliya (sunta A iyo B) ayaa sababa cudur. Waxay kiciyaan bararka iyagoo carqaladeynaya unugyada epithelial-ka mindhicirka. Sunta A waa enterotoxin oo waxyeeleeya xuubka mindhicirka, kordhiya marin-u-helka, iyo soo jiidashada unugyada difaaca jirka ee sii daaya cytokines-ka bararka. Sunta B, oo ah sunta cytotoxin ee xooggan, waxay bartilmaameedsataa unugyada actin cytoskeleton, taasoo keenta wareegidda unugyada, kala-goynta, iyo ugu dambeyntii dhimashada unugyada. Wadajir ahaan, suntaani waxay keenaan dhaawac unug iyo jawaab celin difaac oo adag, taas oo u muuqata colitis, shuban, iyo xaaladaha daran, colitis pseudomembranous - barar daran oo xiidmaha ah.

Sidee ayuu u sameeyaaC. Kala Duwanfaafitaan?

C. Diff si fudud ayuu ugu faafaa. Waxay ku jirtaa isbitaallada, badanaa laga helo ICU-yada, gacmaha shaqaalaha isbitaalka, sagxadaha isbitaalka iyo biraha gacanta, heerkulbeegyada elektaroonigga ah, iyo qalabka kale ee caafimaadka...

Arrimaha Halista ah ee Cudurka Kala Duwan ee C.

• ●Isbitaal dhigista muddada dheer;

• ●Daaweynta antimicrobial-ka;

• ●Wakiilada kemotherabi;

• ●Qalliin dhawaan la sameeyay (gacmaha caloosha, caloosha oo la mariyo, qalliinka mindhicirka);

• ●Nafaqada caloosha iyo mindhicirka;

• ●Caabuqa hore ee C. diff;

Calaamadaha caabuqa C. Diff

C. caabuqa kala duwan wuxuu noqon karaa mid aad u raaxo darro ah. Dadka badankood waxay leeyihiin shuban iyo raaxo la'aan joogto ah oo caloosha ah. Calaamadaha ugu badan waa: shuban, calool xanuun, lallabo, cunto xumo, qandho.

Marka caabuqa C. diff uu sii xumaado, waxaa jiri doona nooc ka sii adag oo C. diff ah oo loo yaqaan colitis, enteritis pseudomembranous iyo xitaa dhimasho.

Baadhista cudurkaee C. Cudurka Diff

Dhaqanka Bakteeriyada:Xasaasi ah laakiin waqti badan qaata (2-5 maalmood), ma kala saari karo noocyada sunta keena iyo kuwa aan sunta ahayn;

Dhaqanka Sunta:waxay aqoonsataa noocyada sunta keena ee keena cudur laakiin waqti badan qaata (3-5 maalmood) oo aan xasaasiyad lahayn;

Ogaanshaha GDH:dhakhso badan (1-2 saacadood) oo kharash-ool ah, aad u xasaasi ah laakiin aan kala saari karin noocyada sunta keena iyo kuwa aan sunta ahayn;

Baaritaanka Naafaynta Sunta Unugga (CCNA): waxay ku ogaataa sunta A iyo B xasaasiyad sare laakiin waxay qaadataa waqti (2-3 maalmood), waxayna u baahan tahay xarumo gaar ah iyo shaqaale tababaran;

Sunta A/B ELISA: Tijaabo fudud oo degdeg ah (1-2 saacadood) oo leh xasaasiyad hoose iyo taban been ah oo soo noqnoqda;

Tijaabooyinka Kordhinta Aashitada Nukliyeerka (NAATs): Degdeg ah (1-3 saacadood) oo aad u xasaasi ah oo gaar ah, oo ogaanaya hiddo-sidayaasha mas'uulka ka ah soo saarista sunta;

Intaa waxaa dheer, baaritaannada sawir-qaadista si loo baaro mindhicirrada, sida CT scans iyo X-rays, ayaa sidoo kale loo isticmaali karaa in lagu caawiyo ogaanshaha C. diff iyo dhibaatooyinka C. diff, sida colitis.

Daaweynta caabuqa kala duwan ee C.

Ikhtiyaar daaweyn oo badan ayaa diyaar u ahC. caabuqa kala duwanHoos waxaa ku qoran xulashooyinka ugu fiican:

• ●Antibiyootikada afka laga qaato sida vancomycin, metronidazole ama fidaxomicin ayaa badanaa la isticmaalaa maadaama daawadu ay dhex mari karto habdhiska dheefshiidka oo ay gaari karto xiidmaha halkaas oo bakteeriyada C. diff ay ku nool yihiin.

• ●Metronidazole-ka xididka laga qaato ayaa loo isticmaali karaa daawaynta haddii caabuqa C. diff uu daran yahay.

• ●Tallaalka microbiota ee saxarada lagu sameeyay ayaa muujiyay waxtarka daaweynta caabuqyada soo noqnoqda ee C. diff iyo caabuqyada daran ee C. diff ee aan ka jawaabin antibiyootikada.

• ●Qalliin ayaa laga yaabaa in loo baahdo kiisaska daran.

Xalka ogaanshaha ee ka imanaya MMT

Annagoo ka jawaabayna baahida loo qabo in si dhakhso ah oo sax ah loo ogaado C. difficile, waxaan soo bandhigaynaa Qalabkayaga cusub ee lagu ogaanayo Aashitada Nucleic ee hidda-wadaha A/B ee sunta Clostridium difficile, annagoo awood siinayna xirfadlayaasha daryeelka caafimaadka inay sameeyaan baaritaan hore oo sax ah iyo taageeridda la dagaallanka caabuqyada laga qaado isbitaalka.

图片链接：

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  ●Xasaasiyadda Sare: Waxay ogaataa sida ugu hooseysa200 CFU/mL,;

• 
  
  ●Bartilmaameed Sax ah: Si sax ah ayuu u aqoonsadaa hidda-wadaha A/B ee sunta ah ee C. adag, isagoo yareynaya waxyaabaha beenta ah ee wanaagsan;

• 
  
  ●Ogaanshaha Tooska ah ee Cudur-sidaha: Wuxuu adeegsadaa baaritaanka aashitada nukliyeer si uu si toos ah u aqoonsado hiddo-sidayaasha sunta, isagoo dejinaya heer dahab ah oo loogu talagalay ogaanshaha.

• 
  
  ●Si buuxda ula jaanqaadi karaqalabka PCR-ga ee caadiga ah oo wax ka qabanaya shaybaadho badan;

Tusaale-ilaa-JawaabXalka Macro & Micro-Test ee Shaybaarka PCR-ka ee Mobile AIO800

 

• ●Is-wada-shaqaynta Muunad ilaa Jawaab - Si toos ah u rarida tuubooyinka muunada asalka ah (1.5–12 mL), taasoo meesha ka saaraysa tuubooyinka gacanta lagu sameeyo. Soo saarista, ballaarinta, iyo ogaanshaha si buuxda ayaa otomaatig ah, taasoo yaraynaysa waqtiga gacanta lagu sameeyo iyo qaladka aadanaha.

• ●Ilaalinta Wasakhowga Siddeed Lakab leh - Hawada jihada, cadaadiska taban, shaandhaynta HEPA, nadiifinta UV, falcelinta shaabadaysan, iyo ilaalin kale oo isku dhafan ayaa ilaaliya shaqaalaha waxayna hubiyaan natiijooyin la isku halleyn karo inta lagu jiro tijaabada wax-soo-saarka sare leh.

Wixii faahfaahin dheeraad ah:

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