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Maxaa sababa caabuqa C. Diff?

Caabuqa C.Diff waxaa keena bakteeriya loo yaqaanClostridioides difficile (C. difficile), kaas oo inta badan si dhib la'aan ah ugu nool xiidmaha. Si kastaba ha ahaatee, marka dheellitirka bakteeriyada mindhicirku uu khalkhal galo, inta badan isticmaalka antibiyootiga ballaaran, C. difficile waxay u koraan si xad dhaaf ah waxayna soo saari karaan sun, taasoo keenta caabuq.

Bakteeriyadani waxay ku jirtaa labadabasun ahiyo qaabab aan sun ahayn, laakiin kaliya noocyada sunta ah (sunnada A iyo B) ayaa keena cudur. Waxay kiciyaan barar iyaga oo carqaladeeya unugyada epithelial mindhicirka. Sunta A waa ugu horrayn enterotoxin oo dhaawaceysa xuubka mindhicirka, kordhinta xajinta, iyo soo jiidata unugyada difaaca ee sii daaya cytokines bararka. Sunta B, cytotoxin ka awood badan, waxay beegsataa cytoskeleton actin ee unugyada, taasoo keenta wareega unugyada, kala go'a, iyo ugu dambeyntii dhimashada unugyada. Si wada jir ah, suntan ayaa sababa dhaawaca unugyada iyo jawaab celin difaac adag, taas oo u muuqata colitis, shuban, iyo xaaladaha daran, colitis pseudomembranous — barar halis ah xiidanka.

Sidee u sameeyaaC. Kala duwanfaafitaan?

C.Diff si fudud ayuu u fidaa. Waxay ku jirtaa isbitaallada, oo inta badan laga helo ICU-yada, gacmaha shaqaalaha isbitaalka, sagxadaha isbitaalka iyo biraha gacanta, heerkulbeegyada elektarooniga ah, iyo qalab kale oo caafimaad...

Arrimaha Khatarta u ah C. Caabuqa Kala Duwan

• ●Cusbataalka muddada dheer;

• ●daawaynta ka hortagga jeermiska;

• ●Wakiilada kiimoterabiga;

• ●Qalliinkii ugu dambeeyay (gacmo-gacmeedka caloosha, marinka caloosha, qalliinka mindhicirka);

• ●Naaso-gastric nafaqada;

• ●Kahor caabuqa C. diff;

Calaamadaha caabuqa C. Diff

C. infekshanka diff wuxuu noqon karaa mid aad u dhib badan. Dadka intooda badan waxaa caloosha ku haya shuban iyo raaxo la'aan. Calaamadaha ugu caansan waa: shuban, calool xanuun, lallabbo, cunto xumo, xummad.

Marka infekshanka C. diff uu sii bato, waxaa soo bixi doona qaab aad u adag oo ah C. diff oo loo yaqaan colitis, pseudomembranous enteritis iyo xitaa dhimasho.

ogaanshahaee C. Diff Infection

Dhaqanka bakteeriyada:Xasaasi ah laakiin waqti badan qaadata (2-5 maalmood), ma kala saari karaan noocyada sunta ah iyo kuwa aan sunta ahayn;

Dhaqanka Sunta:aqoonsada noocyada sunta ah ee sababa cudur laakiin waqti badan qaata (3-5 maalmood) iyo dareen yar;

Ogaanshaha GDH:degdeg ah (1-2hrs) iyo kharash-ool ah, aad xasaasi u ah laakiin aan kala saari karin noocyada sunta ah iyo kuwa aan sunta ahayn;

Baaritaanka Dhexdhexaadnimada Unug Cytotoxicity (CCNA)Waxay ogaataa sun A iyo B oo leh dareen sare laakiin waqti badan qaata (2-3 maalmood), waxayna u baahan tahay tas-hiilaad gaar ah iyo shaqaale tababaran;

Sun A/B ELISAImtixaan fudud oo degdeg ah (1-2hrs) oo leh dareen hoose iyo diidmo been abuur ah oo joogto ah;

Tijaabooyin Kordhinta Ashitada Nukliyeerka (NAATs)Degdeg ah (1-3hrs) oo aad xasaasi u ah & gaar ahaan, ogaanshaha hidda-socodka ka mas'uulka ah soosaarka sunta;

Intaa waxaa dheer, baaritaannada sawirka si loo baaro mindhicirrada, sida CT scans iyo raajada, ayaa sidoo kale loo isticmaali karaa in lagu caawiyo ogaanshaha C. diff iyo dhibaatooyinka C. diff, sida colitis.

Daawaynta caabuqa C. Diff

Doorashooyin badan oo daaweyn ah ayaa diyaar u ahC. kala duwanaansho caabuq. Hoos waxaa ah xulashooyinka ugu fiican:

• ●Antibiyootiga afka laga qaato sida vancomycin, metronidazole ama firaxomicin ayaa caadi ahaan loo isticmaalaa maadaama daawadu ay dhaafi karto habka dheefshiidka oo ay gaarto xiidmaha halka ay bakteeriyada C. diff ku nooshahay.

• ●metronidazole xididka ayaa loo isticmaali karaa daawaynta haddii caabuqa C. diff uu daran yahay.

• ●Ku-tallaalidda saxarada microbiota waxay muujisay waxtarka daaweynta caabuqyada C. diff ee soo noqnoqda iyo caabuqyada C. diff ee daran oo aan ka jawaabin antibiyootiga.

• ●Qaliin ayaa laga yaabaa inay lagama maarmaan u noqoto xaaladaha daran.

Xalka ogaanshaha ee MMT

Iyada oo laga jawaabayo baahida degdegga ah, ogaanshaha saxda ah ee C. difficile, waxaanu soo bandhigaynaa qalabkayaga cusub ee Nucleic Acid Detection Kit ee Clostridium difficile toxin A / B hidda, awoodsiinta xirfadlayaasha daryeelka caafimaadka si ay u sameeyaan baaritaan hore oo sax ah iyo taageeridda dagaalka ka dhanka ah caabuqyada isbitaallada.

图片链接：

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  ●Dareen sare: Wuxuu ogaadaa sida ugu hooseeya200 CFU/ml,;

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  ●Beegsiga saxda ah: Si sax ah u aqoonsada C. difficile toxin A/B hiddo-wadaha, iyada oo yaraynaysa waxtarka beenta ah;

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  ●Ogaanshaha Jidka Tooska ahWaxay isticmaashaa baadhista aashitada nukliyeerka si ay si toos ah u aqoonsato hiddo-wadaha sunta ah, isaga oo dejinaya jaangooyo dahab ah oo lagu baadho.

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  ●Si buuxda ula jaan qaadaQalabka caadiga ah ee PCR ee wax ka qabanaya shaybaaro badan;

Tusaalaha-JawaabtaXalka Makro & Micro-Test AIO800 Mobile PCR Lab

 

• ●Tusaalaha-Jawaab-celinta Automation - Si toos ah ugu shub tuubooyinka muunada asalka ah (1.5-12 mL), baabi'inta dhuumaha gacanta. Soo saarista, kordhinta, iyo ogaanshaha si buuxda ayaa otomaatig ah, taas oo yaraynaysa wakhtiga gacanta iyo khaladka bini'aadamka.

• ●Ilaalinta Wasaqda-Sideeda-Layer - socodka hawada ee jihada, cadaadiska taban, shaandhaynta HEPA, jeermiska UV, falcelinta xidhxidhan, iyo ilaalino kale oo isku dhafan ayaa ilaaliya shaqaalaha oo hubiya natiijooyin la isku halayn karo inta lagu jiro tijaabada sare.

Faahfaahin dheeraad ah:

https://www.mmtest.com/nucleic-acid-detection-kit-for-clostridium-difficile-toxin-ab-gene-fluorescence-pcr-product/

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