PCT/IL-6 La isku daray

PCT waa horudhaca calcitonin, kaas oo ah glycoprotein ka kooban 116 amino acids.Qadarka kelli waa qiyaastii 12.8kd.Ma laha wax dhaqdhaqaaq hormoon ah.Marka la eego xaaladaha jireed, PCT inta badan waa la farsameeyay oo waxaa sir ah unugyada tayroodh C.Inta lagu jiro infekshanka bakteeriyada, macrophages iyo monocytes ee beerka, lymphocytes iyo unugyada endocrine ee sambabada iyo unugyada mindhicirka ayaa isku daraya oo qarsoodi ah qadar badan oo PCT ah oo hoos yimaada ficilka endotoxin, buro necrosis factor-α iyo interleukin-6, taasoo keentay koror weyn. heerarka serum PCT.
Interleukin-6 waa cytokine ay muujiso habka difaaca jirka ee gudaha inta lagu jiro dhaawaca bilowga ah iyo caabuqa.Waxa soo saara fibroblasts, monocytes/macrophages, T-lymphocytes, lymphocytes B, unugyada epithelial, keratinocytes, iyo unugyo burooyin oo kala duwan.IL-6 waxay ka kooban tahay laba silsiladood oo glycoprotein ah, mid waa silsilad α oo miisaankeedu yahay 80kd;Midda kale waa silsilad β ah oo miisaankeedu yahay 130kd[5].Haddii jidhka bini'aadamka uu kiciyo bararka, heerarka IL-6 ayaa si degdeg ah u kacaya, taas oo markaa dhexdhexaadinaysa jawaabta wejiga degdega ah ee beerka waxayna kor u qaadaa soo saarista borotiinnada wajiga degdega ah sida borotiinka C-reactive (CRP) iyo serum amyloid A (SAA). ).Sidaa darteed, IL-6 waa calaamadda ugu horreysa ee kor u kacda marka bararku dhaco.