Cudurrada Neefsashada ee la isku daray
Magaca alaabta
Qalabka Baaritaanka Cudurrada Neefsashada ee HWTS-RT158A (Fluorescence PCR)
Shahaadada
CE
Cudurrada Faafa
Cudurka Fayraska Corona 2019, oo loo yaqaan "Caabuqa Fayraska Corona"'COVID 19', waxaa loola jeedaa oof-wareenka uu keeno cudurka 2019-nCoV. 2019-nCoV waa fayras ka tirsan hidde-sidaha β. COVID-19 waa cudur faafa oo neef-mareenka ah, dadkuna guud ahaan way u nugul yihiin. Waqtigan xaadirka ah, isha caabuqa waxaa inta badan ka soo baxa bukaanada uu ku dhacay 2019-nCoV, dadka qaba cudurka aan calaamadaha lahayn ayaa sidoo kale noqon kara isha caabuqa. Iyada oo lagu saleynayo baaritaanka cudurka faafa ee hadda socda, muddada cudurka waa 1-14 maalmood, inta badan 3-7 maalmood. Qandho, qufac qalalan iyo daal ayaa ah calaamadaha ugu muhiimsan. Bukaanno yar ayaa lahaa calaamado sida ciriiriga sanka, sanka oo dareera, cuna xanuun, myalgia iyo shuban, iwm.
Hargabka, oo loo yaqaan "hargabka", waa cudur neef-mareenka ah oo degdeg ah oo uu keeno fayraska hargabka. Aad ayuu u faafaa. Waxaa badanaa lagu kala qaadaa qufaca iyo hindhisada. Badanaa wuxuu dilaacaa guga iyo jiilaalka. Fayrasyada hargabka waxaa loo qaybiyaa hargabka A (IFV A), hargabka B (IFV B), iyo hargabka C (IFV C) saddex nooc, dhammaantood waxay ka tirsan yihiin fayras dhegdheg leh, waxayna keenaan cudurrada aadanaha inta badan fayrasyada hargabka A iyo B, waa fayras RNA oo hal-xadhig leh, oo kala qaybsan. Fayraska Hargabka A waa caabuq neef-mareen oo degdeg ah, oo ay ku jiraan H1N1, H3N2 iyo noocyo kale, kuwaas oo u nugul isbeddelka iyo faafitaanka adduunka oo dhan. "Shift" waxaa loola jeedaa isbeddelka fayraska hargabka A, taasoo keenta soo ifbaxa "nooc hoose" oo fayras cusub ah. Fayrasyada Hargabka B waxaa loo qaybiyaa laba nooc, Yamagata iyo Victoria. Fayraska Hargabka B wuxuu leeyahay oo keliya isbeddel antigenic ah, wuxuuna ka baxsadaa la socodka iyo baabi'inta nidaamka difaaca jirka aadanaha iyada oo loo marayo isbeddelkiisa. Si kastaba ha ahaatee, xawaaraha isbeddelka fayraska hargabka B waa ka gaabis badan kan fayraska hargabka A ee aadanaha. Fayraska hargabka nooca B wuxuu sidoo kale sababi karaa caabuqyada neefsashada ee aadanaha wuxuuna horseedi karaa cudurro faafa.
Fayraska isku-dhafka neef-mareenka (RSV) waa fayras RNA ah, oo ka tirsan qoyska paramyxoviridae. Waxaa lagu kala qaadaa dhibcaha hawada iyo xiriirka dhow waana cudur-sidaha ugu weyn ee keena caabuqa marinnada neef-mareenka ee hoose ee dhallaanka. Dhallaanka qaba cudurka RSV waxay yeelan karaan boronkiito daran iyo oof-wareen, kuwaas oo la xiriira neefta carruurta. Dhallaanka waxay leeyihiin calaamado daran, oo ay ku jiraan qandho sare, rhinitis, pharyngitis iyo laryngitis, ka dibna bronchiolitis iyo oof-wareen. Carruur yar oo xanuunsan ayaa ku adkaan kara otitis media, pleurisy iyo myocarditis, iwm. Caabuqa marinnada neef-mareenka sare waa calaamadda ugu weyn ee caabuqa dadka waaweyn iyo carruurta waaweyn.
Kanaal
| FAM | SARS-CoV-2 |
| VIC (HEX) | RSV |
| CY5 | IFV A |
| ROX | IFV B |
| Quasar 705 | Xakamaynta Gudaha |
Halbeegyada Farsamada
| Kaydinta | -18℃ |
| Muddada khaanadaha | 12 bilood |
| Nooca Muunada | Suufka afka laga qaato |
| Ct | ≤38 |
| LoD | 2019-nCoV: 300 Nuqullo/mL Fayraska Hargabka A/ Fayraska Hargabka B/ Fayraska isku-dhafka neefsashada: 500 Nuqullo/mL |
| Gaar ahaanshaha | a) Natiijooyinka fal-celinta isdhaafka ah waxay muujinayaan inaysan jirin wax falcelin isdhaaf ah oo u dhexeeya qalabka iyo fayraska fayraska SARSr-CoV ee aadanaha, MERSr-CoV, HCoV-OC43, HCoV-229E, HCoV-HKU1, HCoV-NL63, nooca fayraska parainfluenza 1, 2, 3, rhinovirus A, B, C, chlamydia pneumoniae, enterovirus A, B, C, D, fayraska epstein-barr, fayraska jadeecada, fayraska cytomegalo ee aadanaha, rotavirus, norovirus, fayraska parotitis, fayraska varicella-zoster, legionella, bordetella pertussis, haemophilus influenzae, staphylococcus aureus, streptococcus pneumoniae, streptococcus pyogenes, klebsiella pneumoniae, mycobacterium TB, smoke aspergillus, candida albicans, candida glabrata, pneumocystis jiroveci iyo cryptococcus cusub iyo aashitada genomic genomic ee aadanaha. b) Awoodda ka hortagga faragelinta: mucin-ka la xushay (60mg/mL), 10% (v/v) oo dhiig ah iyo phenylephrine (2mg/mL), oxymetazoline (2mg/mL), sodium chloride (oo ay ku jiraan waxyaabaha ilaaliya) (20mg/mL), beclomethasone (20mg/mL), dexamethasone (20mg/mL), flunisolide (20μg/mL), triamcinolone acetonide (2mg/mL), budesonide (2mg/mL), mometasone (2mg/mL), fluticasone (2mg/mL), histamine hydrochloride (5mg/mL), alpha interferon (800IU/mL), zanamivir (20mg/mL), ribavirin (10mg/mL), oseltamivir (60ng/mL), peramivir (1mg/mL), lopinavir (500mg/mL), ritonavir (60mg/mL), mupirocin (20mg/mL), azithromycin (1mg/mL), ceftriaxone (40μg/mL), meropenem (200mg/mL), levofloxacin (10μg/mL) iyo tobramycin (0.6mg/mL) si loogu sameeyo baaritaanka faragelinta, natiijooyinkuna waxay muujinayaan in walxaha faragelinta leh ee leh xaddiga kor ku xusan aysan lahayn wax falcelin faragelin ah oo ku aaddan natiijooyinka baaritaanka ee jeermiska. |
| Qalabka Khuseeya | Nidaamka PCR-ga ee Waqtiga-dhabta ah ee BioRad CFX96 Nidaamka PCR-ga waqtiga-dhabta ah ee Rotor-Gene Q 5plex HRM Platform |
