BADBAADADA GRAB EE GRAB EE V600E
Magaca wax soo saarka
HWTS-TM007-TM007-Bini-aadamka BRAGE GENT V600E isbadalka qalabka loo yaqaan 'v600e ogaanshaha'
Shahaado
CE / TFDA
Nadiifin
In ka badan 30 nooc oo ah isku dhafka Braf ayaa la helay, oo qiyaastii 90% ay ku yaalliin Exon 15, halkaas oo ay ku yaalliin Exon 15, halkaas oo ay ku yaalliin Exon 15, halkaas oo ay ku yaalliin isbadalka V600E ee loo yaqaan 'V600me', taasi waa, taasina waa booska 1799 ee Ponson 15 lagu beddelo Adenene (a), taasoo dhalisay bedelka valine (v) ee booska 600 oo ay ku jirto cirfiidhada (e) ee sheyga borotiinka. Isbedelada Braf waxaa badanaa laga helaa burooyinka malignant sida melanoma, kansarka mindhicirka, kansarka tayroodh, kansarka sanbabada. Fahmitaanka isbadalka hidda-wadaha ee Braf waxay noqotay baahida loo qabo in la baaro dawooyinka loo yaqaan 'Egff-TKI' ee loo yaqaan 'TIK-TIKIs' iyo Braf-ka 'ee loo yaqaan' Braf 'iyo BRONE TENTION DHESTIVE ee Daaweynta Daaweynta Daroogada ee bukaanka ka faa'iideysan kara bukaannada.
Kanaal
Fa farqad | Ver600e isbadal, xakameyn gudaha ah |
Cayayaanka farsamada
Bakhaar | ≤-18 ℃ |
Shelf-Life | 9 bilood |
Nooca muunadda | paraffin-smikadaha unugyada paraffin |
CV | <5.0% |
Ct | ≤38 |
Dhigid | U adeegso xirmooyinka si aad u ogaato xakameynta tayada tayada leh ee u dhigma. a) Marka loo eego 3ng / μl nooca duurjoogta ah, heerka is-beddelka 1% ayaa lagu ogaan karaa kaydinta falcelinta ee ku habboon; b) Qiyaastii 1% isbadalka, isbadalka 1 × 103Nuqulo / ML ee asalka duurjoogta ah ee 1 × 105Nuqulada / ML waxaa lagu ogaan karaa kaydinta jawaab celinta; c |
Aaladaha lagu dabaqi karo: | Waxaa lagu dabaqay biosystemy-ga ee lagu dabaqay 7500 nidaamyada waqtiga-dhabta ah ee PCRWaxaa lagu dabaqay biosystemy-ga oo lagu dabaqay 7300 waqtiga dhabta ah ee PCR Nidaamyada, QuicestSudio® 5 Nidaamyada PCR-ka waqtiga-dhabta ah Nalalka Firfircoon480 Nidaamka PCR-ka waqtiga-dhabta ah Biorad Cfx96 Nidaamka waqtiga-dhabta ah ee PCR |
Socodka shaqada
DIIWAANGALINTA KHATARTA: QIAGEG's's QIamp DNA DNA (56404), Parffin-CorsDa-ka-soo-saareynta Qalabka Soo-saarista DP330) ee ay soo saartay Tiangen Biotech (Beijing) Co., Ltd.