● Qaaxada Mycobacterium
-
Mycobacterium tuberculosis Nucleic Acid iyo Rifampicin (RIF), Isoniazid Resistance (INH)
Alaabtani waxay ku habboon tahay in la ogaado tayada Mycobacterium tuberculosis DNA ee shaybaarada xaakada bini'aadamka ee vitro, iyo sidoo kale isbeddelka homozygous ee gobolka 507-533 amino acid codon (81bp, gobolka go'aaminta iska caabinta rifampicin) ee hidda-socodka rpoB ee keena qaaxada Mycobacterium iska caabin rifampicin.
-
Mycobacterium Qaaxada Isoniazid Resistance Mutation
Qalabkani wuxuu ku haboon yahay in lagu ogaado tayada goobaha ugu muhiimsan ee isku-beddelka ee shaybaarada xaakada bani'aadamka ee laga soo ururiyay bukaanada Tubercle bacillus positive ah taas oo u horseedda mycobacterium tuberculosis isoniazid caabbinta: Gobolka dhiirigeliyaha InhA -15C>T, -8T>A, -8T>C;Gobolka horumariyaha AhpC -12C>T, -6G>A;isu beddelka qaniisyada ee KatG 315 codon 315G>A, 315G>C .
-
Mycobacterium Tuberculosis iska caabinta Rifampicin
Qalabkani waxa uu ku habboon yahay in lagu ogaado tayada isku-beddelka homozygous ee gobolka 507-533 amino acid codon ee hidda-wadaha rpoB ee keena iska caabbinta Mycobacterium tuberculosis rifampicin.
-
Mycobacterium tuberculosis Nucleic Acid iyo Rifampicin Resistance
Qalabkani waxa uu ku haboon yahay in lagu ogaado tayada DNA-ga ee Mycobacterium tuberculosis DNA-da ee shaybaarada xaakada bini'aadamka ee vitro, iyo sidoo kale isku-bedelka homozygous ee gobolka 507-533 amino acid codon ee hidda-wadaha rpoB ee keena iska caabbinta Mycobacterium tuberculosis rifampicin.
-
Mycobacterium Tuberculosis INH iska caabinta
Qalabkan waxa loo isticmaalaa in si tayo leh loo ogaado isu-beddelka hidda-wadaha ee 315-aad amino acid ee hidda-wadaha katG (K315G>C) iyo beddelka hidda-wadaha gobolka dhiirrigeliye ee hidda-wadaha InhA (- 15 C>T).
-
Mycobacterium Tuberculosis DNA
Waxay ku habboon tahay in si tayo leh loo ogaado DNA-ga Mycobacterium tuberculosis ee shaybaarada xaakada ee bini'aadamka, waxayna ku habboon tahay ogaanshaha kaaliyaha ee caabuqa qaaxada Mycobacterium.
