Mycobacterium Tuberculosis iska caabinta Rifampicin

Sharaxaad Gaaban:

Qalabkani waxa uu ku habboon yahay in lagu ogaado tayada isku-beddelka homozygous ee gobolka 507-533 amino acid codon ee hidda-wadaha rpoB ee keena iska caabbinta Mycobacterium tuberculosis rifampicin.


Faahfaahinta Alaabta

Tags Product

Magaca alaabta

HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Qalabka Ogaanshaha Iska-caabbinta (Fluorescence PCR)

Epidemiology

Rifampicin ayaa si weyn loogu isticmaalay daawaynta bukaanada qaaxada sambabada tan iyo dabayaaqadii 1970-meeyadii, waxayna leedahay saameyn weyn.Waxay ahayd doorashada koowaad ee lagu soo gaabiyo daaweynta kemotherabi ee bukaannada qaaxada sambabada.Iska caabbinta Rifampicin waxaa badanaa sababa isbeddelka hidda-wadaha rpoB.Inkasta oo dawooyinka cusub ee ka hortagga qaaxada ay si joogto ah u soo baxayaan, iyo waxtarka bukaan-socodka ee bukaannada qaaxada sambabada ayaa sidoo kale sii waday inay soo roonaato, weli waxaa jira la'aanta daawooyinka ka hortagga qaaxada, iyo ifafaalaha isticmaalka daroogada aan macquul ahayn ee bukaan-socodka waa mid aad u sarreeya.Sida iska cad, qaaxada Mycobacterium ee bukaanada qaba qaaxada sambabada gabi ahaanba lama dili karo waqti ku haboon, taasoo aakhirka keenta in qofka bukaanka ah uu jidhkiisa iska caabiyo darajooyin kala duwan, siina dheerayso muddada cudurka, kordhisana khatarta dhimashada bukaanka.Qalabkani waxa uu ku habboon yahay ogaanshaha kaaliyaha ee caabuqa qaaxada Mycobacterium iyo ogaanshaha hiddasidaha iska caabinta rifampicin, taas oo waxtar u leh in la fahmo iska caabbinta daawada qaaxada mycobacterium ee uu buka buka, iyo in la siiyo habab caawimo ah oo lagu hago dawooyinka kiliinikada.

Epidemiology

 

Magaca Bartilmaameedka Wariye Quencher
Reaction BufferA Reaction BufferB Reaction BufferC
rpoB 507-514 rpoB 513-520 IS6110 FAM Midna
rpoB 520-527 rpoB 527-533 / CY5 Midna
/ / Xakamaynta gudaha HEX (VIC) Midna

 

Qiyaasaha Farsamada

Kaydinta

≤-18℃ Madow

Nolosha shelf

9 bilood

Nooca Tuunada

xaako

CV

<5

LoD

nooca duurjoogta ah ee rifampicin: 2x103bakteeriyada/ml

mutant homozygous: 2x103bakteeriyada/ml

Gaar ahaan

Waxay ogaataa qaaxada mycobacterium-ka duurjoogta ah iyo goobaha isku-bedelka ee hidde-sideyaasha kale ee iska caabbinta daroogada sida katG 315G>C\A, InhA-15C>T, natiijooyinka baaritaanku waxay muujinayaan wax iska caabin ah oo loo yaqaan 'rifampicin', taas oo macnaheedu yahay inaysan jirin falcelin iskutallaab ah.

Qalabka lagu dabaqi karo:

SLAN-96P Nidaamyada PCR-Waqtiga-dhabta ah (Hongshi Medical Technology Co., Ltd.)

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