● Oncology
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Bani'aadamka TEL-AML1 Isku-beddelka Hiddaha
Qalabkan waxa loo isticmaalaa in lagu ogaado tayada TEL-AML1 hidda-wadaha fusion ee muunadaha dhuuxa lafta bini'aadamka ee vitro.
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Methylated Human NDRG4/SEPT9/SFRP2/BMP3/SDC2 Hid
Qalabka waxaa loogu talagalay in lagu ogaado tayada tayada leh ee methylated NDRG4/SEPT9/SFRP2/BMP3/SDC2 ee unugyada xiidmaha ee xiidmaha ee muunadaha saxarada aadanaha.
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Bani'aadamka BRAF Hida V600E
Xirmadan tijaabada ah waxaa loo isticmaalaa in si tayo leh lagu ogaado isu-beddelka hidda-wadaha BRAF V600E ee muunadaha nudaha paraffin-ku-xidhan ee melanoma ee bini'aadamka, kansarka mindhicirka, kansarka tayroodhka iyo kansarka sanbabada ee vitro.
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Bani'aadamka BCR-ABL Fusion Hid is beddelka
Qalabkani wuxuu ku habboon yahay in lagu ogaado tayada p190, p210 iyo p230 isoforms ee hidda-wadaha fusion BCR-ABL ee muunadaha dhuuxa lafta bini'aadamka.
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Isbeddellada KRAS 8
Qalabkan waxaa loogu talagalay in lagu ogaado tayada tayada ee vitro ee 8 isbeddellada ee codons 12 iyo 13 ee hiddo-wadaha K-ras ee laga soo saaray DNA-da qaybaha baaraffin-ku-xidhan ee bini'aadamka.
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Bani'aadamka EGFR Gene 29 Isbeddellada
Qalabkan waxa loo isticmaalaa in vitro si tayo leh loo ogaado isu-beddellada caadiga ah ee exons 18-21 ee hiddo-wadaha EGFR ee muunado laga soo qaaday bukaannada kansarka sambabada ee unugga yar yar.
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Bani'aadamka ROS1 Fusion Hid is beddelka
Xirmadan waxa loo isticmaalaa in lagu ogaado in vitro lagu ogaanayo tayada 14ka nooc ee isku-bedelka hidda-wadaha ROS1 ee muunadaha kansarka sambabada ee unugyada aan-yaraha ahayn (Shaxda 1).Natiijooyinka baaritaanka waxaa loogu talagalay tixraaca bukaan-socodka oo keliya mana aha in loo isticmaalo saldhigga keliya ee daaweynta gaarka ah ee bukaanka.
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Bani'aadamka EML4-ALK Fusion Hid is beddelka
Qalabkan waxa loo isticmaalaa in si tayo leh lagu ogaado 12 nooc oo beddelaad ah oo EML4-ALK ah hiddo-wadaha isku dhafka ah ee muunado ee bukaannada kansarka sambabada ee unugyada aan yarayn ee gudaha vitro.Natiijooyinka baaritaanka waxaa loogu talagalay tixraaca bukaan-socodka oo keliya mana aha in loo isticmaalo saldhigga keliya ee daaweynta gaarka ah ee bukaanka.Dhakhaatiirtu waa inay sameeyaan go'aanno dhammaystiran oo ku saabsan natiijooyinka baaritaanka oo ku saleysan arrimo ay ka mid yihiin xaaladda bukaanka, calaamadaha daroogada, jawaabta daaweynta, iyo tilmaamayaasha kale ee baaritaanka sheybaarka.
