Bini aadamka Cyp2c19 hiddo-wadaha

Bini-aadamka Cyp2c19 hidde-ku-dhigga polmyrorphorphim-ka ayaa muuqata muuqaalka

Sharraxaadda Gaaban:

Qalabkan waxaa loo isticmaalaa in lagu ogaado fiilada tayo-tareenka ee cudurka polymorphisk ee Cyp2c19 Bilowgii Cyp2C19 * Cyp4 (RS4848 * A), Cyp4 (RS1224 *, 17 (Rs1224550, C.806. > T) gudaha DNA-da Glanomic ee saamballada dhiigga oo dhan.

U dir emaylka

Si faahfaafo

Calaamadaha wax soo saarka

Magaca wax soo saarka

HWTS-GE012A-Aadanaha Cyp2c19 Hante plstrorphism Kit (PCR)

Shahaado

CE / TFDA

Nadiifin

Cyp2c19 waa mid ka mid ah daroogada muhimka ah ee dawooyinka ugu muhiimsan ee enzymes ee qoyska Cym450 qoys. Dheecaanno badan oo daroogada ah iyo ilaa 2% daroogada caafimaad ee ay qaadaan Cyp2c19, sida dheef-shiid kiimikaad xakamaynta isku-darka (omecodogel), anticorogel), iwm. Daawooyinka la xiriira. ISTICMAALKA MADAXWEYNAHA: dhiigga dhiiga. * 17 (RS12248560) waxay kordhin kartaa waxqabadka enzyme ee ay soo saareen Cyp2c19 hidde-wadaha, soosaarka metaboliteska firfircoon, iyo kor u qaadida isku-darka isku-darka Platelet-ka oo kordhay. Dadka qaba dheef-shiid kiimikaad gaabis ah oo daroogada ah, qaadashada qiyaasta caadiga ah ee daroogada muddo dheer waxay sababi doonaan waxyeelo sunta ah oo sunta ah Marka loo eego kala duwanaanshaha shaqsiyeed ee dheef-shiid kiimikaadka daroogada ee u dhigma, waxaa guud ahaan loo qaybiyaa afar phelra, oo ah dheef-shiid kiimikaad aan dhakhso badan (um, * 1 / * 17), dheef-shiid kiimikaad dhaqso ah (RM, * 1 / * 1) ), dheef-shiid kiimikaad dhexe (IM, * 1 / * 2, * 1 / * 3), dheef-galaada dheef-shiid kiimikaad (PM, * 2 / * 2, * 2 / * 3, 3 / * 3. * 3 / * 3).

Kanaal

Fa farqad	Cyp2c1c19 * 2
Cy5	Cyp2c9 * 3
Rox	Cyp2c1c19 * 17
Vic / hex	IC

Cayayaanka farsamada

Bakhaar	Dareere: ≤-18 ℃
Shelf-Life	12 bilood
Nooca muunadda	Edta oo cusub edta lidka ku ah daawada
CV	≤5.0%
Dhigid	1.0ng / μL
Si gaar ah	Ma jiro wax-ka-qabasho iskutallaab ah oo ay ku jiraan taxanaha kale ee isdaba joog ah (Cyp2C9 hiddo-wadaha) ee bini-aadamka. Isbeddellada Cyp2c1c19 * 23, Cyp2c19 * 24 iyo Cyp2c1c19 * 25 Goobaha ka baxsan kala-soocidda khasabkan wax saameyn ah kuma yeeshaan ogaanshaha ogaanshaha xirmada.
Aaladaha lagu dabaqi karo	Waxaa lagu dabaqay biosystemy-ga ee lagu dabaqay 7500 nidaamyada waqtiga-dhabta ah ee PCR Waxaa lagu dabaqay bio-yariyada bio-yada lagu dabaqay 7500 oo si dhakhso leh u ah nidaamyada PCR-ga Jadwalka PCRSSDUDDUDO®5 Nidaamyada PCR Nidaamyada 'Slacan-96p' ee waqtiga dhabta ah ee PCR Nalalka Firfircoon480 Nidaamka PCR-ka waqtiga-dhabta ah Sadarka 9600 oo lagu daray nidaamka ogaanshaha PCR-ka waqtiga-dhabta ah MA-6000 baaskiil-ku-meel-gaadhka waqtiga-ku-meel-gaarka ah Biorad Cfx96 Nidaamka waqtiga-dhabta ah ee PCR Biorad Cfx Opus 96 Nidaamka PCR-ka waqtiga-dhabta ah

Socodka shaqada

Soosaarka lagu taliyay Reaggent: macro & macro-Imtixaan Guud DNA / RNA KIT (HWTS-3019) (oo loo isticmaali karo macro-maka macro-ek011) oo ay tahay macro-macro-med-thewort Co., Ltd. Soosaarka waa in loo soosaaraa iyadoo loo eegayo tilmaamaha. Mugga muunad soosaarka ah waa 200μl, oo mugga ka-jawaabidda ee lagula taliyo waa 100μl.

Soosaarka lagula taliyo: Wizard® Geerta nadiifinta DNA (Catalog maya. Waa in loo soosaaraa iyada oo loo eegayo tilmaamaha soosaarka, iyo mugga soo saarista ee lagu taliyay waa 200 μl oo mugga okna karinta ayaa ah 160 μL.

Hore: Bini-aadamka tagaagta dawooyinka ah b27 nucleic acid

Xiga: Bini-aadamka Cyp2c9 iyo VKORC1 HIT POLY lystrorphism

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